Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguus of F344 rats
نویسندگان
چکیده
Binbin Yan, Lihua Li, Scott W. Harden, David Gozal, Ying Lin, William B. Wead, Robert D. Wurster, and Zixi (Jack) Cheng Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida; Department of Physiology, Harbin Medical University, Harbin, China; Department of Pediatrics, Kosair Children’s Hospital Research Institute, and Department of Physiology and Biophysics, University of Louisville, Kentucky; and Department of Physiology, Loyola University Stritch School of Medicine, Maywood, Illinois
منابع مشابه
Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguous of F344 rats.
Chronic intermittent hypoxia (CIH), as occurs in sleep apnea, impairs baroreflex-mediated reductions in heart rate (HR) and enhances HR responses to electrical stimulation of vagal efferent. We tested the hypotheses that HR responses to activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and N-methyl-D-aspartate (NMDA) receptors in the nucleus ambiguous (NA) are reduced i...
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